Why proteomics is not the new genomics and the future of mass spectrometry in cell biology

Mass spectrometry (MS) is an essential part of the cell biologist’s proteomics toolkit, allowing analyses at molecular and system-wide scales. However, proteomics still lag behind genomics in popularity and ease of use. We discuss key differences between MS-based -omics and other booming -omics technologies and highlight what we view as the future of MS and its role in our increasingly deep understanding of cell biology.