The CAES mission is to address critical science and engineering issues that will help resolve the grand challenges associated with providing an appropriate mix of energy technologies needed to address critical U.S. and global energy needs. Although CAES will have an emphasis on nuclear energy, it will also address other energy areas that are critical to ensuring U.S. energy security, including affordability, limited environmental impacts, and leadership in the global energy arena. Energy technologies to be addressed include those for nuclear, hydrogen, and fossil fuels (coal, oil, and gas) and the full spectrum of renewable energy sources. CAES is part of the Idaho National Laboratory of the US Department of Energy.

The CBCD is developing new ways to design, build and analyze biological circuits. Biological circuits control information flow in biological systems, and as such are a core area of Information Science and Technology. We combine the experimental biologist's desire to abstract the key principles from the richness and diversity of biological circuits, the physicist's sense of measurement and of simple underlying mechanisms, and the engineer's aesthetic of "to build is to understand." The study of circuits cuts across vast areas of biology, from biochemistry, biophysics and genetics, to cell and developmental biology, to neurobiology and ecology. Understanding how to design and build circuits is crucial for the next generation of bioengineering.

The mission of the Center for Biomedical Engineering (CBE) is to combine engineering with molecular and cellular biology to develop new approaches to biomedical technology and to foster research in the rapidly growing discipline of Biological Engineering. With five new members this past year, over 45 CBE faculty (from departments in the MIT Schools of Engineering and Science, as well as the Whitehead institute, Harvard and Boston University Medical Schools and the Harvard-MIT Division of Health Sciences and Technology) carry out interdisciplinary, multi-investigator research programs within CBE. This faculty research provides a training environment for a new generation of graduate and undergraduate students in Bioengineering, at the interface between Engineering and Biology.

The Center for Bits and Atoms (CBA) is a campus-wide program involving faculty from the Departments of Physics, Chemistry, Mathematics, Computer Science, Biology, Brain and Cognitive Sciences, and Mechanical, Electrical, and Biological Engineering, as well as the Media Laboratoryall working at the boundary between physical science and computer science. The research program spans from the experimental investigation of molecular mechanisms to digitize fabrication (analogous to the earlier digitization of communications and computation), to the theoretical study of mathematical principles to program enormously complex engineered systems, with practical application in personal fabrication around the world. CBA was launched in 2002 by a $13.75 million award from the National Science Foundation (NSF), which has enabled the creation of a unique facility for input and output from nanometers to meters. Along with the NSF support, CBA receives funding from partner government agencies and from its industrial sponsors.

Centered at UC Berkeley, CITRIS incubates research on problems that have a major impact on the economy, quality of life, and future success of California: conserving energy; education; saving lives, property, and productivity in the wake of disasters; boosting transportation efficiency; advancing diagnosis and treatment of disease; and expanding business growth through much richer personalized information services. Solutions to many of these problems have a common IT feature: at their core they depend on highly-distributed, reliable, and secure information systems that can evolve and adapt to radical changes in their environment, delivering information services that adapt to the people and organizations that need them. It is this feature that is at the heart of the initial research agenda for CITRIS.

Welcome to the Center for Polymer Studies (CPS), a scientific visualization research center in the Physics Department and Science and Mathematics Education Center at Boston University. We are devoted to interdisciplinary research in aspects of polymer, random, and fractal systems and we utilize our expertise in this area to develop experimental and computational materials for high school and undergraduate education. Interdisciplinary science research including cardiac dynamics, statistical mechanisms of Alzheimer's Disease, and simulations of liquid water. Education outreach projects include curriculum development, teacher professional development, and building collaborations with other researchers.

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IN 1986, CALTECH ESTABLISHED an interdisciplinary Ph.D. program to study problems arising at the interface between neurobiology, electrical engineering, computer science, and physics. The unifying theme of today's program is the relationship between the physical structure of a computational system (molecular, neuronal or electronic hardware), the dynamics of its operation, and the computational problems that it can efficiently solve. The creation of this multidisciplinary program stems from progress on several fronts: the analysis of complex biological systems at the molecular, neuronal, network and cognitive levels, the modeling and analysis of artificial neural networks and their learning abilities and the emergence of neuromorphic engineering as an independent discipline.

Computational mechanics is the analysis of structures and fields using finite element, finite difference, and finitevolume methods to predict the behavior of materials, engineering structures and also their possible failuresmodes and criteria while in the design process.

The Cooperative Association for Internet Data Analysis (CAIDA) is a collaborative undertaking among organizations in the commercial, government, and research sectors aimed at promoting greater cooperation in the engineering and maintenance of a robust, scalable global Internet infrastructure. CAIDA provides a neutral framework to support cooperative technical endeavors.

The CubeSat Project developed, by California Polytechnic State University San Luis Obispo and Stanford University's Space Systems Development Lab, creates launch opportunities for universities previously unable to access space. With over 60 universities and high school participating in the CubeSat program, the educational benefits are tremendous. Students, through hands on work, will develop the necessary skills and experience needed to succeed in the Aerospace industry. The CubeSat program also benefits private firms and government by providing a low-cost way of flying payloads in space. All while creating important educational opportunities for future leaders of industry.

Digital Life (DL) is a Media Lab consortium that conducts basic research on technologies and techniques that spur human expression as well as social and economic activity. It operates in close collaboration with industrial and research partners to explore ideas in the context of their use, recognizing that change occurs when the magic of invention is driven by existing or emergent human behavior. Currently, the program has three broad directions: [1] Organic Networks, which combines a re-examination of the physics of radio to construct viral communications systems with the intelligence at the ends. The grassroots nature of these systems allows people to innovate both locally and organically, much as the PC migrated innovation from the mainframe to the individual; [2] 10X, which considers technologies that can improve human activity by an order of magnitude, including bionics, robotic and cognitive assistants, and human learning. 10X envisions intimately connected analytical and mechanical systems working with, as well as for, human interests; and [3] Common-Sense Computing, which is an attempt to reinvigorate artificial intelligence by developing a cognitive architecture that can support many features of human intelligent thinking. From this base, we aim to develop systems that are robust to changing environments, assumptions, and problems.

DIMES is a distributed scientific research project, aimed to study the structure and topology of the Internet, with the help of a volunteer community (similar in spirit to projects such as SETI@Home).

The Basic Energy Sciences (BES) program supports fundamental research in focused areas of the natural sciences in order to expand the scientific foundations for new and improved energy technologies and for understanding and mitigating the environmental impacts of energy use. BES also discovers knowledge and develops tools to strengthen national security. The BES program plans, constructs, and operates major scientific user facilities to serve researchers from universities, national laboratories, and industrial laboratories.

The Office of Civilian Radioactive Waste Management (OCRWM) is a program of the U.S. Department of Energy assigned to develop and manage a federal system for disposing of spent nuclear fuel from commercial nuclear reactors and high-level radioactive waste from national defense activities.