Description: Genetic linkage analysis is a statistical method that is used to associate functionality of genes to their location on chromosomes. The main idea is that markers which are found in vicinity on the chromosome have a tendency to stick together when passed on to offsprings. Thus, if some disease is often passed to offsprings along with specific markers, then it can be concluded that the gene(s) which are responsible for the disease are located close on the chromosome to these markers. Superlink is a computer program that performs exact genetic linkage analysis with input-output relationships similar to those in standard genetic linkage programs Linkage, Fastlink v4.1, Tlinkage, Vitesse v2.0, and Genehunter v2.1. Superlink can run larger files than previous programs.

Posted: 05/21/06

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